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Farran, Arij B.
Senior Administrative Assistant
Faculty Research Overviews
Raychelle Burks
![Cell phone showing onscreen options.](/cas/chemistry/images/burks-phone.jpg)
The research team of泭Dr. Burks is focused on the development of colorimetric and luminescent sensor arrays for the detection of analytes of mainly forensic and national security interests with accompanying image and chemometric analysis.泭Dr. Burks collaborates with colleagues in a variety of fields to provide application-specific sensing systems employing portable, imaging-based detection.泭
Selected Publications
Azaldegui, C., Aguilar, G., Enriquez, S., Madonna, C., Parish Fisher, C. and Burks, R. (2021), . J Forensic Sci, 66: 1085-1093.泭
Durham Brooks T, Burks R, Doyle E, Meysenburg M, Frey T (2021) . PLoS ONE 16(5): e0241946.泭
Michael J.泭Kangas,泭Raychelle M.泭Burks,泭Jordyn泭Atwater,泭Rachel M.泭Lukowicz,泭Pat泭Williams泭&泭Andrea E.泭Holmes泭(2017)泭,泭47:2,泭138-153.
Stefano Costanzi
![Ribbon structure for mutant murine acetylcholinesterase bound to the acetylcholine analogue 4k-TMA (PDB ID: 2HA0)](/cas/chemistry/images/cn-2018-00148d_0006.png)
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Dr. Costanzis research interests rest at the nexus of chemistry, policy, security, and the application of computational methods to address practical problems. Focusing on , he studies arms control, nonproliferation, and counterproliferation strategies, policies, and practices with the goal of conceptualizing and developing solutions and tools to strengthen them, through a blend of chemistry, information technology, and science-based policy.
Douglas Fox
![Highmagnification SEM of the cross sections of the mixed wCNC/tCNC films with a) 0%, b) 1%, and c) 10% by mass tCNCs](/cas/chemistry/images/last.png)
Dr. Fox develops commercial and industrial products using sustainable materials. Our lab currently investigates new flame retardants, coatings, fiber reinforced plastics, and the health and safety (EHS) of nanomaterials.
Matthew Hartings
![Various 3D printed objects](/cas/chemistry/images/3dp_1.jpg)
泭揖泭
Dr. Hartings has two main laboratory research projects: 1) The use of 3D printing to create chemically reactive objects and 2) The development of novel environmental and biological sensors based off of stimulus-responsive materials. Dr. Hartings is also active in studying and communicating about all of the wonderful chemistry we do at home in our kitchens while we cook.
Selected Publications
SELECTED PUBLICATIONS
Monika Konaklieva
Dr. Konaklievas main research interest is in the area of using organic synthesis and evaluation towards the generation of new antibacterial, antiviral agents and lipoprotein metabolism modulators. Within this research, the group aims to develop efficient and environmentally friendly synthetic approaches for their preparation. Interdisciplinary projects are a main focus in the Konaklievas group, involving organic synthesis/medicinal chemistry, biochemistry, and structure-based drug design.泭
Santiago Toledo
Research in the泭Toledo lab focuses on two main themes:泭a.泭the泭synthesis and reactivity of泭biomimetic models of metalloenzymes with the goal of understanding the泭role that metalloenzymes play in disease states泭including cancer development and neurodegenerative diseases;泭b.泭the design of bioinspired catalysts泭to promote challenging oxidative transformations for use on environmentally relevant degradation of organic compounds.
Selected Publications
Kirsch, K; Little, M. E.; Cundari, T.R.; El-Shaer, E.; Barone, G.; Lynch, V. M.;泭Toledo, S.A.*泭Direct O2 mediated oxidation of a Ni(ii)N3O structural model complex for the active site of nickel acireductone dioxygenase (Ni-ARD): characterization, biomimetic reactivity, and enzymatic implications.泭Dalton Transactions, 2024,泭.
Toledo, S.; Yan Poon, P.C.; Gleaves, M.; Rees, J. Rogers, D. Kaminsky, W.; Kovacs, J.泭Increasing Reactivity by Incorporating -Acceptor Ligands into Coordinatively Unsaturated Thiolate-Ligated Iron(II) Complexes. Inorganica Chimica Acta,泭2021, 524,120422.泭
Blade, G.A. ; Parveen, R.; Jaimes, J.L. ; Ilustre, W. ; Salda簽a,D. ; Ivan, D.A. ; Lynch,V.M. Cundari, T.R.;泭Toledo,S.*泭A family of structural and functional models for the active site of a unique dioxygenase: Acireductone dioxygenase (ARD).泭Journal of Inorganic Biochemistry,泭2020,泭212, 111253.
Healy, E. F.; Flores, R.; Lynch, V.M.;泭Toledo, S.*泭Protein dynamics of [CuZn]superoxide dismutase (SOD1): How protein motions at the global and local levels impact the reactivity of SOD1.泭Journal of Inorganic Biochemistry,泭2020, 210, 111161.泭
Healy, E.; Roth-Rodriguez, A. ;泭Toledo, S.泭A model for gain of function in superoxide dismutase.泭Biochemistry and Biophysics Reports.泭2020, 21, 100728.泭
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Toledo, S.A.*; Dubas, J.M.泭A Learner-Centered Grading Method Focuses on Reaching Proficiency with Course Learning Outcomes.泭Journal of Chemical Education,泭2017,泭94,泭1043-1050.
Toledo, S.A.*; Dubas, J.M.泭Encouraging Higher-Order Thinking in General Chemistry by Scaffolding Student Learning Using Marzano's Taxonomy.泭Journal of Chemical Education,泭2016, 93, 64-69.
Alexander Zestos
Dr. Zestos is a bioanalytical chemist who utilizes electrochemistry and chromatographic methods for bioanalysis. Research from his group focuses on the measuring rapid neurochemical changes of dopamine, serotonin, and other neurotransmitters. His work has vast implications for studying drugs of abuse, obesity, diabetes, depression, and many other diseases and behavioral states.
Selected Publications
An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling
Shouzhong Zou
![Alloys and carbon layers from Zhou's publication](/cas/images/sz.gif)
Dr. Zou develops catalysts for hydrogen fuel cells and conversion of carbon dioxide to organic fuels using sustainable materials.泭
Research News
Recent Grants
Douglas Fox received $36,519 of additional funding from the US Endowment for Forestry & Communities, Inc. for his project titled "14C Labeled Cellulose Nanofibrils for EHS Studies. The new total award for this project is $89,377.
Hanning Chen was awarded $35,000 from George Washington University for his project, entitled: Collaborative Research: Integrated Experimental and Computational Studies for Understanding the Interplay of Photoreactive Materials and Persistent Contaminants.
Hanning Chen was awarded $18,000 from his prime funder, George Washington University, for his project, entitled: Development of Graphitic-Carbon-Nitride-Based Antimicrobial Nanomaterials for Safe Food Processing and Packaging.
Hanning Chen was awarded $11,250, as an incremental fund, from Utah State University, prime funder Honda Research Institute USA, Inc., for his project, named: Systematic Exploration of MEG Materials for Solar Energy Conversion. He is expecting a total funding of $45,000.
Hanning Chen received a grant for $18,000 from US Department of Agriculture for a project titled "Development of Graphitic-Carbon-Nitride-Based Antimicrobial Nanomaterials for Safe Food Processing and Packaging."
Hanning Chen received a grant for $35,000 from the National Science Foundation for his project "SusChem: Collaborative Research: Integrated Experimental and Computational Studies for Understanding the Interplay of Photoreactive Materials and Persistent Contaminants."
Alexander G. Zestos received a $24,841 grant award from the National Institutes of Health (NIH) for his work on the Mechanisms of Amphetamine Abuse.
Alexander Zestos received a grant for $84,938 from Microprobes for Life Science Inc. (prime Sponsor NIH) for his work on "Multielectrode Arrays for Neurotransmitter Detection with Fast Scan Cyclic Voltammetry.
Alexander Zestos泭received a Small Business Technology Transfer (STTR) grant award from the National Institutes of Health (NINDS/NIMH) for his work on multielectrode arrays for neurotransmitter detection for $144,992.
Zestos received泭a Small Business Innovation Research (SBIR) grant from 泭the National Institute of Health, which will support his collaboration with a local company, Microprobes.
Zestos received泭a grant for $50,000 from the National Science Founation (NSF) for his research泭"I-Corps: Multielectrode Array Biosensor Development.泭
Matthew Hartings泭received泭a grant for泭$17,020 from the泭Parker Hannifin Corporation for the work on his泭project regarding泭Nitro Cold Brew.
Douglas Fox泭was awarded a $149,900 grant from the National Institute of Standards and Technology (NIST) for his Tailoring Cellulose Nanomaterial Surface Properties for Improved Polymer Stress Transfer."
Fox泭received $4,505, and is expected to receive additional funding of $23,191, from FiberLean Technologies for his research titled "Nanocellulose Labeling to Track Migration from Paper."
Fox泭received泭a grant for泭$6,176 from FiberLean Technologies泭for the project "Nanocellulose泭Migration from Food Coating."